Book

Innovations in Oral, Injectable, and Transdermal Drug Delivery Systems

Subject Area: Pharmacy, Medical, Dental Science
Pages: 234
Published On: 10-Nov-2025
Online Since: 10-Nov-2025

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Author(s): Abhinav Garg, Dr. Sarfaraz Ahmad (B.Pharm, M.Pharm, PhD), Mr. Swapnil Deelip Phalak, Dr. Sudhahar Dharmalingam, Dr. Sonali

Email(s): abhinav.spk@gmail.com , sriyazahmad@jazanu.edu.sa , Emailsdphalak@gmail.com , sonali.ccp@cgc.edu.in

Address: Abhinav Garg Associate Director Onesource Speciality Pharma Ltd, Bangalore
Dr. Sarfaraz Ahmad (B.Pharm, M.Pharm, PhD) Assistant Professor Pharmacy Practice Research Unit (PPRU), Department of Clinical Practice, College of Pharmacy, Jazan University, Jazan, KSA
Mr. Swapnil Deelip Phalak Assistant Professor Konkan Gyanpeeth Rahul Dharkar Col
lege of Pharmacy and Research Institute Karjat 410201
Dr. Sudhahar Dharmalingam, Professor & Head, Department of Pharmaceutical Chemistry and Analysis, Nehru College of Pharmacy (affiliated to Kerala University of Health Sciences, Thrissur) Pampady, Nila Gardens, Thiruvilwamala, Thrissur Dist, Kerala – 680588
Dr. Sonali Assistant Professor Chandigarh College of Pharmacy, Landran, Mohali Pin 140307

Published In:   Book, Innovations in Oral, Injectable, and Transdermal Drug Delivery Systems

Year of Publication:  November, 2025

Online since:  November 10, 2025

DOI: Not Available

ABSTRACT:
Injectable drug delivery systems play a pivotal role in modern therapeutics by enabling rapid onset of action, precise dosing, and targeted delivery of bioactive compounds. This overview examines the fundamental principles, classifications, and technological advancements in injectable formulations, including solutions, suspensions, emulsions, and depot systems. Key considerations such as sterility, biocompatibility, pharmacokinetics, and patient safety are discussed in the context of intravenous, intramuscular, subcutaneous, and intradermal routes. Innovations in sustained-release injectables, liposomal carriers, and biodegradable polymers have expanded the scope of injectable therapies, particularly in oncology, immunology, and chronic disease management. Understanding these systems is essential for developing safe, effective, and patient-centric injectable products.


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REFERENCES

1.     Baryakova, T. H., Pogostin, B. H., Langer, R., & McHugh, K. J. (2023). Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems. Nature Reviews Drug Discovery, 22(5), 387-409.

2.     Ezike, T. C., Okpala, U. S., Onoja, U. L., Nwike, C. P., Ezeako, E. C., Okpara, O. J., ... & Nwanguma, B. C. (2023). Advances in drug delivery systems, challenges and future directions. Heliyon, 9(6).

3.     Jacob, S., Nair, A. B., Shah, J., Sreeharsha, N., Gupta, S., & Shinu, P. (2021). Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management. Pharmaceutics, 13(3), 357.

4.     Jeong, W. Y., Kwon, M., Choi, H. E., & Kim, K. S. (2021). Recent advances in transdermal drug delivery systems: A review. Biomaterials research, 25(1), 24.

5.     Kafle, U., Agrawal, S., & Dash, A. K. (2022). Injectable nano drug delivery systems for the treatment of breast cancer. Pharmaceutics, 14(12), 2783.

6.     Khan, M. I., Hossain, M. I., Hossain, M. K., Rubel, M. H. K., Hossain, K. M., Mahfuz, A. M. U. B., & Anik, M. I. (2022). Recent progress in nanostructured smart drug delivery systems for cancer therapy: a review. ACS applied bio materials, 5(3), 971-1012.

7.     Lee, H., Song, C., Baik, S., Kim, D., Hyeon, T., & Kim, D. H. (2018). Device-assisted transdermal drug delivery. Advanced drug delivery reviews, 127, 35-45.

8.     Liang, Y., Zhao, X., Ma, P. X., Guo, B., Du, Y., & Han, X. (2019). pH-responsive injectable hydrogels with mucosal adhesiveness based on chitosan-grafted-dihydrocaffeic acid and oxidized pullulan for localized drug delivery. Journal of colloid and interface science, 536, 224-234.

9.     Merino, S., Martín, C., Kostarelos, K., Prato, M., & Vázquez, E. (2015). Nanocomposite hydrogels: 3D polymer–nanoparticle synergies for on-demand drug delivery. ACS nano, 9(5), 4686-4697.

10.  Norouzi, M., Nazari, B., & Miller, D. W. (2016). Injectable hydrogel-based drug delivery systems for local cancer therapy. Drug discovery today, 21(11), 1835-1849.

11.  Park, H., Otte, A., & Park, K. (2022). Evolution of drug delivery systems: From 1950 to 2020 and beyond. Journal of Controlled Release, 342, 53-65.

12.  Raj, V. K., Mazumder, R. U. P. A., & Madhra, M. O. N. I. K. A. (2020). Ocular drug delivery system: challenges and approaches. Int J Appl Pharm, 12(5), 49-57.

13.  Riahi, R., Tamayol, A., Shaegh, S. A. M., Ghaemmaghami, A. M., Dokmeci, M. R., & Khademhosseini, A. (2015). Microfluidics for advanced drug delivery systems. Current Opinion in Chemical Engineering, 7, 101-112.

14.  Sheikh, A. A. (2016). Injectable controlled release drug delivery systems. Asian Journal of Pharmaceutics (AJP), 10(04).

15.  Sheikh, A. A., & Sheikh, S. R. (2016). Advanced injectable drug delivery system: A brief review. System, 9(1), 11.






Author/Editor Information

Dr Sumit Bhatt

Assistant Professor and PhD Scholar in Oral and Maxillofacial Surgery at Rajasthan Dental College and Hospital, Nirwan University, Jaipur

Dr. Mrunal Dave

Associate dentist “Bethlehem Smile Design” Bethlehem, Pennsylvania USA.

Dr. Suyash Pratap Singh

Dr. Suyash Pratap Singh is an Endodontist and a Senior Lecturer at the Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Bareilly

Dr. S. Shruti

Dr. S. Shruti is an Associate Professor and Acting Head in the Department of Rasashastra evam Bhaishajyakalpana at Sri Ganganagar College of Ayurvedic Science and Hospital, Sri Ganganagar, Rajasthan, India