Global Research Connect Publication

We provide unique ISBN, professional Cover Design, wide Coverage and Indexing.


  Book

Innovations in Oral, Injectable, and Transdermal Drug Delivery Systems

Subject Area: Pharmacy, Medical, Dental Science
Pages: 234
Published On: 10-Nov-2025
Online Since: 10-Nov-2025

 Read More >>

 Book Chapter

ADVANCES IN INJECTABLE DRUG DELIVERY TECHNOLOGIES

Author(s): Dr. T. Deborah Paripuranam, Dr. Challa. Taraka Ramarao, Prof. (Dr.) Nalini Kanta Sahoo, Dr. Kumar Gourav, Dr. Sweety Lanjhiyana

Email(s): debovermi@gmail.com , tarak.pharm60@gmail.com , sahoo.nalini@gmail.com , drkumargourav89@gmail.com , slanjh@gmail.com

Address: Dr. T. Deborah Paripuranam Assistant professor Institute address: Nadar Saraswathi College of Arts and science,Theni Pin : 625531
Dr. Challa. Taraka Ramarao Professor Department of Pharmaceutical Technology. Sri Venkateswara College of Pharmacy,Etcherla, Andhra Pradesh -532410
Prof. (Dr.) Nalini Kanta Sahoo Professor & Dean, Faculty of Pharmaceutical Sciences, Rama University Rama City, Mandhana, Kanpur (Uttar Pradesh) - 209 217
Dr. Kumar Gourav Assistant professor Institute - AIMMMCR Bhilai, chhatisgarh 490020
Dr. Sweety Lanjhiyana Principal & Professor Institute of Pharmaceutical Studies, Sakri Bilaspur (CG)-495001

Published In:   Book, Innovations in Oral, Injectable, and Transdermal Drug Delivery Systems

Year of Publication:  November, 2025

Online since:  November 10, 2025

DOI: Not Available

 View HTML        View PDF

ABSTRACT:
Injectable drug delivery systems have undergone transformative advancements, driven by the need for improved therapeutic efficacy, patient adherence, and precision medicine. Recent innovations include long-acting formulations, enzyme-responsive hydrogels, and smart delivery platforms that respond to physiological cues. Technologies such as peptoid-peptide hydrogels enable in situ gelation and sustained drug release, minimizing dosing frequency and enhancing bioavailability. Additionally, nanocarriers, liposomes, and microparticles are being engineered for targeted delivery, reducing systemic toxicity and improving pharmacokinetics. These systems are increasingly tailored for chronic conditions, oncology, and immunotherapy, with a focus on biodegradable materials, stimuli-responsive mechanisms, and minimally invasive administration. The integration of biomaterials science, molecular engineering, and computational modeling continues to push the boundaries of injectable therapeutics, offering promising avenues for personalized and sustained drug delivery.


Keywords:

Cite this article:
working


1.     Xu, L., Wang, X., Liu, Y., Yang, G., Falconer, R. J., & Zhao, C. X. (2022). Lipid nanoparticles for drug delivery. Advanced NanoBiomed Research, 2(2), 2100109.

2.     Vigata, M., Meinert, C., Hutmacher, D. W., & Bock, N. (2020). Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques. Pharmaceutics, 12(12), 1188.

3.     Liang, Y., Zhao, X., Ma, P. X., Guo, B., Du, Y., & Han, X. (2019). pH-responsive injectable hydrogels with mucosal adhesiveness based on chitosan-grafted-dihydrocaffeic acid and oxidized pullulan for localized drug delivery. Journal of colloid and interface science, 536, 224-234.

4.     Bordbar-Khiabani, A., & Gasik, M. (2022). Smart hydrogels for advanced drug delivery systems. International Journal of Molecular Sciences, 23(7), 3665.

5.     Gidwani, B., & Vyas, A. (2015). A comprehensive review on cyclodextrin‐based carriers for delivery of chemotherapeutic cytotoxic anticancer drugs. BioMed research international, 2015(1), 198268.

6.     Alavi, M., Karimi, N., & Safaei, M. (2017). Application of various types of liposomes in drug delivery systems. Advanced pharmaceutical bulletin, 7(1), 3.

7.     Calixto, G. M. F., Bernegossi, J., De Freitas, L. M., Fontana, C. R., & Chorilli, M. (2016). Nanotechnology-based drug delivery systems for photodynamic therapy of cancer: a review. Molecules, 21(3), 342.

8.     Luo, Z., Dai, Y., & Gao, H. (2019). Development and application of hyaluronic acid in tumor targeting drug delivery. Acta Pharmaceutica Sinica B, 9(6), 1099-1112.

9.     Fenton, O. S., Olafson, K. N., Pillai, P. S., Mitchell, M. J., & Langer, R. (2018). Advances in biomaterials for drug delivery. Advanced Materials, 30(29), 1705328.

10.  Bruschi, M. L. (2015). Strategies to modify the drug release from pharmaceutical systems. Woodhead Publishing.

11.  Adawiyah, N., Moniruzzaman, M., Hawatulaila, S., & Goto, M. (2016). Ionic liquids as a potential tool for drug delivery systems. MedChemComm, 7(10), 1881-1897.

12.  Ha, D., Yang, N., & Nadithe, V. (2016). Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges. Acta Pharmaceutica Sinica B, 6(4), 287-296.

13.  Homayun, B., Lin, X., & Choi, H. J. (2019). Challenges and recent progress in oral drug delivery systems for biopharmaceuticals. Pharmaceutics, 11(3), 129.

14.  Fam, S. Y., Chee, C. F., Yong, C. Y., Ho, K. L., Mariatulqabtiah, A. R., & Tan, W. S. (2020). Stealth coating of nanoparticles in drug-delivery systems. Nanomaterials, 10(4), 787.

15.  Chu, D., Dong, X., Shi, X., Zhang, C., & Wang, Z. (2018). Neutrophil‐based drug delivery systems. Advanced materials, 30(22), 1706245.




Author/Editor Information

Dr Sumit Bhatt

Assistant Professor and PhD Scholar in Oral and Maxillofacial Surgery at Rajasthan Dental College and Hospital, Nirwan University, Jaipur

Dr. Mrunal Dave

Associate dentist “Bethlehem Smile Design” Bethlehem, Pennsylvania USA.

Dr. Suyash Pratap Singh

Dr. Suyash Pratap Singh is an Endodontist and a Senior Lecturer at the Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Bareilly

Dr. S. Shruti

Dr. S. Shruti is an Associate Professor and Acting Head in the Department of Rasashastra evam Bhaishajyakalpana at Sri Ganganagar College of Ayurvedic Science and Hospital, Sri Ganganagar, Rajasthan, India